Special PD Edition:
In Case You Missed It!
May 2024

This month’s newsletter highlights a selection of recently published peer-reviewed articles featuring peritoneal dialysis (PD).

Peritoneal Dialysis Recent Findings

Assisted peritoneal dialysis: Position paper for the ISPD

Physical, cognitive, and behavioral disabilities are common barriers to self-care PD. Authors highlight situations when assisted PD could help overcome these barriers and expand PD therapy availability to individuals not deemed suitable otherwise. The authors propose a new systematized approach to assisted PD by way of alternative funding models, patient indications, operational models, and payment justifications.

Social determinants of health and dialysis modality selection in patients with advanced chronic kidney disease: A retrospective cohort study

A retrospective study of 981 patients with advanced chronic kidney disease (CKD), referred to the Ottawa Hospital Multi-Care Kidney Clinic and who progressed to end-stage kidney disease between 2010 to 2021. Social determinants of health were examined and assessed in relation to initial dialysis modality selection, with a discussion of potential strategies to mitigate PD preference based primarily on education level, employment, marital status, and living situation.

The impact of icodextrin on the outcomes of incident peritoneal dialysis patients

The outcomes of 725 incident end-stage kidney disease patients, and who were on PD for at least 90 days over a 12-year period (2007-2018), were reviewed. Risks of death, technique failure, and the first episode of peritonitis were analyzed and compared between patients prescribed Icodextrin for ≥ 50% (190 patients) of their time on PD therapy versus ≤50% (535) of their time on PD therapy.

A time-averaged serum bicarbonate-based nomogram to predict the probability of residual kidney function preservation for patients undergoing peritoneal dialysis

A retrospective study of 151 PD patients found that higher baseline values of residual glomerular filtration rate, total Kt/V, and higher time-average serum bicarbonate levels were associated with a better probability of preservation of residual kidney function (RKF). These protective criteria were assigned point values based on the magnitude of each criterion, and their associated RKF protection, in the first and second year of PD use. The authors created a nomogram to show the probability of predicted preservation of RKF based on the sum of point values for each criterion (see Figure 1).

APM5060 Rev.A

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